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The Pregnane X Receptor: From Bench to Bedside
BACKGROUND: The pregnane X receptor (PXR; NR1I2), a member of the nuclear receptor superfamily, regulates the expression of metabolic enzymes and transporters involved in the response of mammals to their chemical environment. OBJECTIVE: To summarize the functions and clinical implications of PXR. ME...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2535920/ https://ncbi.nlm.nih.gov/pubmed/18624678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17425255.4.7.895 |
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