Tumor regionality in the mouse intestine reflects the mechanism of loss of Apc function

Inherited colorectal cancer syndromes in humans exhibit regional specificity for tumor formation. By using mice with germline mutations in the adenomatous polyposis coli gene (Apc) and/or DNA mismatch repair genes, we have analyzed the genetic control of tumor regionality in the mouse small intestin...

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Bibliographic Details
Main Authors: Haigis, Kevin M., Hoff, Peter D., White, Alanna, Shoemaker, Alex R., Halberg, Richard B., Dove, William F.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC470749/
https://ncbi.nlm.nih.gov/pubmed/15210940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403338101
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