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Tumor regionality in the mouse intestine reflects the mechanism of loss of Apc function

Inherited colorectal cancer syndromes in humans exhibit regional specificity for tumor formation. By using mice with germline mutations in the adenomatous polyposis coli gene (Apc) and/or DNA mismatch repair genes, we have analyzed the genetic control of tumor regionality in the mouse small intestin...

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Detalhes bibliográficos
Main Authors: Haigis, Kevin M., Hoff, Peter D., White, Alanna, Shoemaker, Alex R., Halberg, Richard B., Dove, William F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC470749/
https://ncbi.nlm.nih.gov/pubmed/15210940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403338101
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