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Differential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on nicotine versus cocaine self-administration and relapse in squirrel monkeys

RATIONALE: Group II metabotropic glutamate receptors (mGluR2 and mGluR3) have been suggested to play an important role in mediation of drug-reinforced behaviors, as well as in the mechanisms underlying relapse in abstinent subjects. The prototypical mGluR2/3 agonist, LY379268, has been shown to atte...

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Detalhes bibliográficos
Publicado no:Psychopharmacology (Berl)
Main Authors: Justinova, Zuzana, Le Foll, Bernard, Redhi, Godfrey H., Markou, Athina, Goldberg, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706511/
https://ncbi.nlm.nih.gov/pubmed/26149611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-015-3994-y
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