Attenuating Nicotine Reinforcement and Relapse by Enhancing Endogenous Brain Levels of Kynurenic Acid in Rats and Squirrel Monkeys

The currently available antismoking medications have limited efficacy and often fail to prevent relapse. Thus, there is a pressing need for newer, more effective treatment strategies. Recently, we demonstrated that enhancing endogenous levels of kynurenic acid (KYNA, a neuroinhibitory product of try...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Secci, Maria E, Auber, Alessia, Panlilio, Leigh V, Redhi, Godfrey H, Thorndike, Eric B, Schindler, Charles W, Schwarcz, Robert, Goldberg, Steven R, Justinova, Zuzana
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518900/
https://ncbi.nlm.nih.gov/pubmed/28139681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2017.21
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