Mouse Susceptibility to Anthrax Lethal Toxin Is Influenced by Genetic Factors in Addition to Those Controlling Macrophage Sensitivity

Bacillus anthracis lethal toxin (LT) produces symptoms of anthrax in mice and induces rapid lysis of macrophages (Mφ) derived from certain inbred strains. We used nine inbred strains and two inducible nitric oxide synthase (iNOS) knockout C57BL/6J strains polymorphic for the LT Mφ sensitivity Kif1C...

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Dettagli Bibliografici
Pubblicato in:Infect Immun
Autori principali: Moayeri, Mahtab, Martinez, Nathaniel W., Wiggins, Jason, Young, Howard A., Leppla, Stephen H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2004
Soggetti:
Host Response and Inflammation
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC470648/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15271901/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.8.4439-4447.2004
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