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Mouse Susceptibility to Anthrax Lethal Toxin Is Influenced by Genetic Factors in Addition to Those Controlling Macrophage Sensitivity

Bacillus anthracis lethal toxin (LT) produces symptoms of anthrax in mice and induces rapid lysis of macrophages (Mφ) derived from certain inbred strains. We used nine inbred strains and two inducible nitric oxide synthase (iNOS) knockout C57BL/6J strains polymorphic for the LT Mφ sensitivity Kif1C...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Moayeri, Mahtab, Martinez, Nathaniel W., Wiggins, Jason, Young, Howard A., Leppla, Stephen H.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2004
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC470648/
https://ncbi.nlm.nih.gov/pubmed/15271901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.8.4439-4447.2004
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