Mouse Susceptibility to Anthrax Lethal Toxin Is Influenced by Genetic Factors in Addition to Those Controlling Macrophage Sensitivity

Bacillus anthracis lethal toxin (LT) produces symptoms of anthrax in mice and induces rapid lysis of macrophages (Mφ) derived from certain inbred strains. We used nine inbred strains and two inducible nitric oxide synthase (iNOS) knockout C57BL/6J strains polymorphic for the LT Mφ sensitivity Kif1C...

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Detaylı Bibliyografya
Yayımlandı:Infect Immun
Asıl Yazarlar: Moayeri, Mahtab, Martinez, Nathaniel W., Wiggins, Jason, Young, Howard A., Leppla, Stephen H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2004
Konular:
Host Response and Inflammation
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC470648/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15271901/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.8.4439-4447.2004
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