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Eukaryotic Translation Initiation Factor 5A (EIF5A) Regulates Pancreatic Cancer Metastasis by Modulating RhoA and Rho-associated Kinase (ROCK) Protein Expression Levels

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers with an overall survival rate of less than 5%. The poor patient outcome in PDAC is largely due to the high prevalence of systemic metastasis at the time of diagnosis and lack of effective therapeutics that target disseminated ce...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Fujimura, Ken, Choi, Sunkyu, Wyse, Meghan, Strnadel, Jan, Wright, Tracy, Klemke, Richard
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4706006/
https://ncbi.nlm.nih.gov/pubmed/26483550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.687418
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