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Exploded view of higher order G-quadruplex structures through click-chemistry assisted single-molecule mechanical unfolding

Due to the long-range nature of high-order interactions between distal components in a biomolecule, transition dynamics of tertiary structures is often too complex to profile using conventional methods. Inspired by the exploded view in mechanical drawing, here, we used laser tweezers to mechanically...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Selvam, Sangeetha, Yu, Zhongbo, Mao, Hanbin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4705664/
https://ncbi.nlm.nih.gov/pubmed/26626151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1326
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