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Development of squaraine based G-quadruplex ligands using click chemistry

The G-quadruplex (G4) structures of nucleic acids are considered to play an intrinsic role in gene expression. To this end, the development of new G4 ligands has attracted extensive research interests towards potential applications as G4-targeted drugs and molecular probes. To date, the majority of...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Xin, Wei, Yongbiao, Bing, Tao, Liu, Xiangjun, Zhang, Nan, Wang, Junyan, He, Junqing, Jin, Bing, Shangguan, Dihua
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500484/
https://ncbi.nlm.nih.gov/pubmed/28684846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04344-x
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