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Development of squaraine based G-quadruplex ligands using click chemistry

The G-quadruplex (G4) structures of nucleic acids are considered to play an intrinsic role in gene expression. To this end, the development of new G4 ligands has attracted extensive research interests towards potential applications as G4-targeted drugs and molecular probes. To date, the majority of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Zhang, Xin, Wei, Yongbiao, Bing, Tao, Liu, Xiangjun, Zhang, Nan, Wang, Junyan, He, Junqing, Jin, Bing, Shangguan, Dihua
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500484/
https://ncbi.nlm.nih.gov/pubmed/28684846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04344-x
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