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Development of squaraine based G-quadruplex ligands using click chemistry

The G-quadruplex (G4) structures of nucleic acids are considered to play an intrinsic role in gene expression. To this end, the development of new G4 ligands has attracted extensive research interests towards potential applications as G4-targeted drugs and molecular probes. To date, the majority of...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Zhang, Xin, Wei, Yongbiao, Bing, Tao, Liu, Xiangjun, Zhang, Nan, Wang, Junyan, He, Junqing, Jin, Bing, Shangguan, Dihua
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500484/
https://ncbi.nlm.nih.gov/pubmed/28684846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04344-x
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