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Development of squaraine based G-quadruplex ligands using click chemistry

The G-quadruplex (G4) structures of nucleic acids are considered to play an intrinsic role in gene expression. To this end, the development of new G4 ligands has attracted extensive research interests towards potential applications as G4-targeted drugs and molecular probes. To date, the majority of...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Zhang, Xin, Wei, Yongbiao, Bing, Tao, Liu, Xiangjun, Zhang, Nan, Wang, Junyan, He, Junqing, Jin, Bing, Shangguan, Dihua
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5500484/
https://ncbi.nlm.nih.gov/pubmed/28684846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04344-x
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