Structure and Stability of Higher-Order Human Telomeric Quadruplexes

G-quadruplex formation in the sequences 5′-(TTAGGG)(n) and 5′(TTAGGG)(n)TT (n=4,8,12) was studied using circular dichroism, sedimentation velocity, differential scanning calorimetry and molecular dynamics simulations. Sequences containing 8 and 12 repeats formed higher-order structures with two and...

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Huvudupphovsmän: Petraccone, Luigi, Spink, Charles, Trent, John O., Garbett, Nichola C., Mekmaysy, Chongkham S., Giancola, Concetta, Chaires, Jonathan B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3244555/
https://ncbi.nlm.nih.gov/pubmed/22082001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja209192a
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