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An integrated molecular dynamics and experimental study of higher order human telomeric quadruplexes

Structural knowledge of telomeric DNA is critical for understanding telomere biology and for the utilization of telomeric DNA as a therapeutic target. Very little is known about the structure of long human DNA sequences that may form more than one quadruplex unit. Here we report a combination of mol...

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Autors principals: Petraccone, Luigi, Garbett, Nichola, Chaires, Jonathan B., Trent, John O.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131549/
https://ncbi.nlm.nih.gov/pubmed/20095044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.21392
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