G-Quadruplex and i-Motif Are Mutually Exclusive in ILPR Double-Stranded DNA

G-quadruplex has demonstrated its biological functions in vivo. Although G-quadruplex in single-stranded DNA (ssDNA) has been well characterized, investigation of this species in double-stranded DNA (dsDNA) lags behind. Here we use chemical footprinting and laser-tweezers-based single-molecule appro...

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Autors principals: Dhakal, Soma, Yu, Zhongbo, Konik, Ryan, Cui, Yunxi, Koirala, Deepak, Mao, Hanbin
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2012
Matèries:
Nucleic Acids
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368138/
https://ncbi.nlm.nih.gov/pubmed/22713573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.04.024
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