Direct experimental evidence for quadruplex–quadruplex interaction within the human ILPR

Here we report the analysis of dual G-quadruplexes formed in the four repeats of the consensus sequence from the insulin-linked polymorphic region (ACAGGGGTGTGGGG; ILPR(n)(=4)). Mobilities of ILPR(n)(=4) in nondenaturing gel and circular dichroism (CD) studies confirmed the formation of two intramol...

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Main Authors: Schonhoft, Joseph D., Bajracharya, Rabindra, Dhakal, Soma, Yu, Zhongbo, Mao, Hanbin, Basu, Soumitra
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2009
Teme:
Structural Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691825/
https://ncbi.nlm.nih.gov/pubmed/19324891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp181
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