Heterogeneous alleles comprising G6PD deficiency trait in West Africa exert contrasting effects on two major clinical presentations of severe malaria

BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD) deficiency exhibits considerable allelic heterogeneity which manifests with variable biochemical and clinical penetrance. It has long been thought that G6PD deficiency confers partial protection against severe malaria, however prior genetic associ...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Shah, Shivang S., Rockett, Kirk A., Jallow, Muminatou, Sisay-Joof, Fatou, Bojang, Kalifa A., Pinder, Margaret, Jeffreys, Anna, Craik, Rachel, Hubbart, Christina, Wellems, Thomas E., Kwiatkowski, Dominic P.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704392/
https://ncbi.nlm.nih.gov/pubmed/26738565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-015-1045-0
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados