Screening for Recently Selected Alleles by Analysis of Human Haplotype Similarity

There is growing interest in the use of haplotype-based methods for detecting recent selection. Here, we describe a method that uses a sliding window to estimate similarity among the haplotypes associated with any given single-nucleotide polymorphism (SNP) allele. We used simulations of natural sele...

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Detalhes bibliográficos
Main Authors: Hanchard, Neil A., Rockett, Kirk A., Spencer, Chris, Coop, Graham, Pinder, Margaret, Jallow, Muminatou, Kimber, Martin, McVean, Gil, Mott, Richard, Kwiatkowski, Dominic P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society of Human Genetics 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1380214/
https://ncbi.nlm.nih.gov/pubmed/16385459
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