A genetic association study in The Gambia using tagging polymorphisms in the major histocompatibility complex (MHC) class III region implicates a HLA-B associated transcript 2 (BAT2) polymorphism in severe malaria susceptibility

The tumour necrosis factor (TNF) gene and other genes flanking it in the major histocompatibility complex (MHC) class III region are potentially important mediators of both immunity and pathogenesis of malaria. We investigated the association of severe malaria with eleven haplotype tagging-polymorph...

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Main Authors: Diakite, Mahamadou, Clark, Taane G., Auburn, Sarah, Campino, Susana G, Fry, Andrew E, Green, Angela, Morris, Andrew P., Richardson, Anna, Jallow, Muminatou, Sisay-Joof, Fatou, Pinder, Margaret, Kwiatkowski, Dominic P., Rockett, Kirk A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992315/
https://ncbi.nlm.nih.gov/pubmed/19039607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-008-0597-2
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