TLR9 polymorphisms in African populations: no association with severe malaria, but evidence of cis-variants acting on gene expression

BACKGROUND: During malaria infection the Toll-like receptor 9 (TLR9) is activated through induction with plasmodium DNA or another malaria motif not yet identified. Although TLR9 activation by malaria parasites is well reported, the implication to the susceptibility to severe malaria is not clear. T...

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Detalhes bibliográficos
Main Authors: Campino, Susana, Forton, Julian, Auburn, Sarah, Fry, Andrew, Diakite, Mahamadou, Richardson, Anna, Hull, Jeremy, Jallow, Muminatou, Sisay-Joof, Fatou, Pinder, Margaret, Molyneux, Malcolm E, Taylor, Terrie E, Rockett, Kirk, Clark, Taane G, Kwiatkowski, Dominic P
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660361/
https://ncbi.nlm.nih.gov/pubmed/19284650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-8-44
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