TLR9 polymorphisms in African populations: no association with severe malaria, but evidence of cis-variants acting on gene expression

BACKGROUND: During malaria infection the Toll-like receptor 9 (TLR9) is activated through induction with plasmodium DNA or another malaria motif not yet identified. Although TLR9 activation by malaria parasites is well reported, the implication to the susceptibility to severe malaria is not clear. T...

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Autori principali: Campino, Susana, Forton, Julian, Auburn, Sarah, Fry, Andrew, Diakite, Mahamadou, Richardson, Anna, Hull, Jeremy, Jallow, Muminatou, Sisay-Joof, Fatou, Pinder, Margaret, Molyneux, Malcolm E, Taylor, Terrie E, Rockett, Kirk, Clark, Taane G, Kwiatkowski, Dominic P
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660361/
https://ncbi.nlm.nih.gov/pubmed/19284650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-8-44
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