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Heterologous Expression and Functional Characterization of the Exogenously Acquired Aminoglycoside Resistance Methyltransferases RmtD, RmtD2, and RmtG

The exogenously acquired 16S rRNA methyltransferases RmtD, RmtD2, and RmtG were cloned and heterologously expressed in Escherichia coli, and the recombinant proteins were purified to near homogeneity. Each methyltransferase conferred an aminoglycoside resistance profile consistent with m(7)G1405 mod...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Corrêa, Laís L., Witek, Marta A., Zelinskaya, Natalia, Picão, Renata C., Conn, Graeme L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704232/
https://ncbi.nlm.nih.gov/pubmed/26552988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02482-15
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