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Heterologous Expression and Functional Characterization of the Exogenously Acquired Aminoglycoside Resistance Methyltransferases RmtD, RmtD2, and RmtG

The exogenously acquired 16S rRNA methyltransferases RmtD, RmtD2, and RmtG were cloned and heterologously expressed in Escherichia coli, and the recombinant proteins were purified to near homogeneity. Each methyltransferase conferred an aminoglycoside resistance profile consistent with m(7)G1405 mod...

詳細記述

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Corrêa, Laís L., Witek, Marta A., Zelinskaya, Natalia, Picão, Renata C., Conn, Graeme L.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704232/
https://ncbi.nlm.nih.gov/pubmed/26552988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02482-15
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