Yüklüyor......
Model-Based Evaluation of Higher Doses of Rifampin Using a Semimechanistic Model Incorporating Autoinduction and Saturation of Hepatic Extraction
Rifampin is a key sterilizing drug in the treatment of tuberculosis (TB). It induces its own metabolism, but neither the onset nor the extent of autoinduction has been adequately described. Currently, the World Health Organization recommends a rifampin dose of 8 to 12 mg/kg of body weight, which is...
Kaydedildi:
| Yayımlandı: | Antimicrob Agents Chemother |
|---|---|
| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology
2015
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4704145/ https://ncbi.nlm.nih.gov/pubmed/26552972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01830-15 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|