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Pharmacokinetics of Pyrazinamide and Optimal Dosing Regimens for Drug-Sensitive and -Resistant Tuberculosis

Pyrazinamide is used in the treatment of tuberculosis (TB) because its sterilizing effect against tubercle bacilli allows the shortening of treatment. It is part of standard treatment for drug-susceptible and drug-resistant TB, and it is being considered as a companion drug in novel regimens. The ai...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Chirehwa, Maxwell T., McIlleron, Helen, Rustomjee, Roxana, Mthiyane, Thuli, Onyebujoh, Philip, Smith, Peter, Denti, Paolo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527644/
https://ncbi.nlm.nih.gov/pubmed/28607022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00490-17
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