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Peptide binding to a bacterial signal peptidase visualized by peptide tethering and carrier-driven crystallization
Bacterial type I signal peptidases (SPases) are membrane-anchored serine proteases that process the signal peptides of proteins exported via the Sec and Tat secretion systems. Despite their crucial importance for bacterial virulence and their attractiveness as drug targets, only one such enzyme, Lep...
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| Publicado no: | IUCrJ |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4704075/ https://ncbi.nlm.nih.gov/pubmed/26870377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2052252515019971 |
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