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Thioredoxin as a fusion tag for carrier-driven crystallization

Structural investigations are frequently hindered by difficulties in obtaining diffracting crystals of the target protein. Here, we report the crystallization and structure solution of the U2AF homology motif (UHM) domain of splicing factor Puf60 fused to Escherichia coli thioredoxin A. Both modules...

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Detalhes bibliográficos
Main Authors: Corsini, Lorenzo, Hothorn, Michael, Scheffzek, Klaus, Sattler, Michael, Stier, Gunter
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2590909/
https://ncbi.nlm.nih.gov/pubmed/18780816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.037564.108
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