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Expression, purification and crystallization of a membrane-associated, catalytically active type I signal peptidase from Staphylococcus aureus
Staphylococcus aureus infections are becoming increasingly difficult to treat as they rapidly develop resistance to existing antibiotics. Bacterial type I signal peptidases are membrane-associated, cell-surface serine proteases with a unique catalytic mechanism that differs from that of eukaryotic e...
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| Publicat a: | Acta Crystallogr F Struct Biol Commun |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
International Union of Crystallography
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4304750/ https://ncbi.nlm.nih.gov/pubmed/25615971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X1402603X |
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