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Structure and Activity of Streptococcus pyogenes SipA: A Signal Peptidase-Like Protein Essential for Pilus Polymerisation

The pili expressed on the surface of the human pathogen Streptococcus pyogenes play an important role in host cell attachment, colonisation and pathogenesis. These pili are built from two or three components, an adhesin subunit at the tip, a major pilin that forms a polymeric shaft, and a basal pili...

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Detalhes bibliográficos
Main Authors: Young, Paul G., Proft, Thomas, Harris, Paul W. R., Brimble, Margaret A., Baker, Edward N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049620/
https://ncbi.nlm.nih.gov/pubmed/24911348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099135
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