Structural Model for Covalent Adhesion of the Streptococcus pyogenes Pilus through a Thioester Bond

The human pathogen Streptococcus pyogenes produces pili that are essential for adhesion to host surface receptors. Cpa, the adhesin at the pilus tip, was recently shown to have a thioester-containing domain. The thioester bond is believed to be important in adhesion, implying a mechanism of covalent...

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Detaylı Bibliyografya
Asıl Yazarlar: Linke-Winnebeck, Christian, Paterson, Neil G., Young, Paul G., Middleditch, Martin J., Greenwood, David R., Witte, Gregor, Baker, Edward N.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2014
Konular:
Protein Structure and Folding
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879542/
https://ncbi.nlm.nih.gov/pubmed/24220033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.523761
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