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Disruption of Cytochrome c Oxidase Function Induces Warburg Effect and Metabolic Reprogramming
Defects in mitochondrial oxidative phosphorylation complexes, altered bioenergetics and metabolic shift are often seen in cancers. Here we show a role for the dysfunction of electron transport chain component, cytochrome c oxidase (CcO) in cancer progression. We show that genetic silencing of the Cc...
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| 發表在: | Oncogene |
|---|---|
| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4703574/ https://ncbi.nlm.nih.gov/pubmed/26148236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.227 |
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