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Specific Inhibition of MicroRNA Processing Using L-RNA Aptamers

In vitro selection was used to obtain L-RNA aptamers that bind the distal stem-loop of various precursor microRNAs (pre-miRs). These L-aptamers, termed “aptamiRs”, bind their corresponding pre-miR target through highly specific tertiary interactions rather than Watson–Crick pairing. Formation of a p...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Am Chem Soc
Egile Nagusiak: Sczepanski, Jonathan T., Joyce, Gerald F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703082/
https://ncbi.nlm.nih.gov/pubmed/26652064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b06696
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