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An L-RNA Aptamer That Binds and Inhibits Ribonuclease
L-RNA aptamers were developed that bind to barnase ribonuclease and thereby inhibit the function of the enzyme. These aptamers were obtained by first carrying out in vitro selection of D-RNAs that bind to the full-length synthetic D-enantiomer of barnase, then reversing the mirror and preparing L-RN...
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| Publicado no: | Chem Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4656138/ https://ncbi.nlm.nih.gov/pubmed/26590636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2015.09.017 |
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