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Binding of a Structured D-RNA Molecule by an L-RNA Aptamer
An L-RNA aptamer was developed that binds the natural D-form of the HIV-1 trans-activation responsive (TAR) RNA. The aptamer initially was obtained as a D-aptamer against L-TAR RNA through in vitro selection. Then the corresponding L-aptamer was prepared by chemical synthesis and used to bind the de...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3804424/ https://ncbi.nlm.nih.gov/pubmed/23977945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja406634g |
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