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Ligand-dependent Exponential Amplification of Self-replicating RNA Enzymes
A general analytical method for the detection of target ligands has been developed, based on a special class of self-replicating aptazymes. These “autocatalytic aptazymes” are generated by linking an aptamer domain to the catalytic domain of a self-replicating RNA enzyme. Ligand-dependent self-repli...
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| Publicado no: | Methods Enzymol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5103853/ https://ncbi.nlm.nih.gov/pubmed/25605379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2014.10.030 |
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