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Ligand-dependent Exponential Amplification of Self-replicating RNA Enzymes

A general analytical method for the detection of target ligands has been developed, based on a special class of self-replicating aptazymes. These “autocatalytic aptazymes” are generated by linking an aptamer domain to the catalytic domain of a self-replicating RNA enzyme. Ligand-dependent self-repli...

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Foilsithe in:Methods Enzymol
Main Authors: Olea, Charles, Joyce, Gerald F.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5103853/
https://ncbi.nlm.nih.gov/pubmed/25605379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2014.10.030
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