Specific induction of endogenous viral restriction factors using CRISPR/Cas-derived transcriptional activators

Whereas several mammalian proteins can restrict the replication of HIV-1 and other viruses, these are often not expressed in relevant target cells. A potential method to inhibit viral replication might therefore be to use synthetic transcription factors to induce restriction factor expression. In pa...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Bogerd, Hal P., Kornepati, Anand V. R., Marshall, Joy B., Kennedy, Edward M., Cullen, Bryan R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2015
Konular:
PNAS Plus
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4703010/
https://ncbi.nlm.nih.gov/pubmed/26668372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516305112
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