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Specific induction of endogenous viral restriction factors using CRISPR/Cas-derived transcriptional activators
Whereas several mammalian proteins can restrict the replication of HIV-1 and other viruses, these are often not expressed in relevant target cells. A potential method to inhibit viral replication might therefore be to use synthetic transcription factors to induce restriction factor expression. In pa...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4703010/ https://ncbi.nlm.nih.gov/pubmed/26668372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516305112 |
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