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Opposing effects of TIGAR- and RAC1-derived ROS on Wnt-driven proliferation in the mouse intestine
Reactive oxygen species (ROS) participate in numerous cell responses, including proliferation, DNA damage, and cell death. Based on these disparate activities, both promotion and inhibition of ROS have been proposed for cancer therapy. However, how the ROS response is determined is not clear. We exa...
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| Foilsithe in: | Genes Dev |
|---|---|
| Main Authors: | , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Cold Spring Harbor Laboratory Press
2016
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4701978/ https://ncbi.nlm.nih.gov/pubmed/26679840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.271130.115 |
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