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Opposing effects of TIGAR- and RAC1-derived ROS on Wnt-driven proliferation in the mouse intestine

Reactive oxygen species (ROS) participate in numerous cell responses, including proliferation, DNA damage, and cell death. Based on these disparate activities, both promotion and inhibition of ROS have been proposed for cancer therapy. However, how the ROS response is determined is not clear. We exa...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Genes Dev
Main Authors: Cheung, Eric C., Lee, Pearl, Ceteci, Fatih, Nixon, Colin, Blyth, Karen, Sansom, Owen J., Vousden, Karen H.
פורמט: Artigo
שפה:Inglês
יצא לאור: Cold Spring Harbor Laboratory Press 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701978/
https://ncbi.nlm.nih.gov/pubmed/26679840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.271130.115
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