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Opposing effects of TIGAR- and RAC1-derived ROS on Wnt-driven proliferation in the mouse intestine
Reactive oxygen species (ROS) participate in numerous cell responses, including proliferation, DNA damage, and cell death. Based on these disparate activities, both promotion and inhibition of ROS have been proposed for cancer therapy. However, how the ROS response is determined is not clear. We exa...
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| Publicado no: | Genes Dev |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4701978/ https://ncbi.nlm.nih.gov/pubmed/26679840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.271130.115 |
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