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TIGAR, TIGAR, burning bright

Cancers cells shift their metabolism towards glycolysis in order to help them support the biosynthetic demands necessary to sustain cell proliferation and growth, adapt to stress and avoid excessive reactive oxygen species (ROS) accumulation. While the p53 tumor suppressor protein is known to inhibi...

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Detalhes bibliográficos
Main Authors: Lee, Pearl, Vousden, Karen H, Cheung, Eric C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892023/
https://ncbi.nlm.nih.gov/pubmed/24383451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2049-3002-2-1
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