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TIGAR, TIGAR, burning bright

Cancers cells shift their metabolism towards glycolysis in order to help them support the biosynthetic demands necessary to sustain cell proliferation and growth, adapt to stress and avoid excessive reactive oxygen species (ROS) accumulation. While the p53 tumor suppressor protein is known to inhibi...

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Autori principali: Lee, Pearl, Vousden, Karen H, Cheung, Eric C
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3892023/
https://ncbi.nlm.nih.gov/pubmed/24383451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2049-3002-2-1
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