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Modulation of intracellular ROS levels by TIGAR controls autophagy

The p53-inducible TIGAR protein functions as a fructose-2,6-bisphosphatase, promoting the pentose phosphate pathway and helping to lower intracellular reactive oxygen species (ROS). ROS functions in the regulation of many cellular responses, including autophagy—a response to stress conditions such a...

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Detalhes bibliográficos
Main Authors: Bensaad, Karim, Cheung, Eric C, Vousden, Karen H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736014/
https://ncbi.nlm.nih.gov/pubmed/19713938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.242
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