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Modulation of intracellular ROS levels by TIGAR controls autophagy
The p53-inducible TIGAR protein functions as a fructose-2,6-bisphosphatase, promoting the pentose phosphate pathway and helping to lower intracellular reactive oxygen species (ROS). ROS functions in the regulation of many cellular responses, including autophagy—a response to stress conditions such a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2736014/ https://ncbi.nlm.nih.gov/pubmed/19713938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.242 |
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