TIGAR Is Required for Efficient Intestinal Regeneration and Tumorigenesis

Regulation of metabolic pathways plays an important role in controlling cell growth, proliferation, and survival. TIGAR acts as a fructose-2,6-bisphosphatase, potentially promoting the pentose phosphate pathway to produce NADPH for antioxidant function and ribose-5-phosphate for nucleotide synthesis...

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Detalhes bibliográficos
Main Authors: Cheung, Eric C., Athineos, Dimitris, Lee, Pearl, Ridgway, Rachel A., Lambie, Wendy, Nixon, Colin, Strathdee, Douglas, Blyth, Karen, Sansom, Owen J., Vousden, Karen H.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682186/
https://ncbi.nlm.nih.gov/pubmed/23726973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.05.001
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