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Protection against Experimental Cryptococcosis following Vaccination with Glucan Particles Containing Cryptococcus Alkaline Extracts

A vaccine capable of protecting at-risk persons against infections due to Cryptococcus neoformans and Cryptococcus gattii could reduce the substantial global burden of human cryptococcosis. Vaccine development has been hampered though, by lack of knowledge as to which antigens are immunoprotective a...

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Publicado en:mBio
Main Authors: Specht, Charles A., Lee, Chrono K., Huang, Haibin, Tipper, Donald J., Shen, Zu T., Lodge, Jennifer K., Leszyk, John, Ostroff, Gary R., Levitz, Stuart M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Microbiology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701832/
https://ncbi.nlm.nih.gov/pubmed/26695631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01905-15
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