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Robust Stimulation of Humoral and Cellular Immune Responses following Vaccination with Antigen-Loaded β-Glucan Particles

β-Glucan particles (GPs) are purified Saccharomyces cerevisiae cell walls treated so that they are primarily β1,3-d-glucans and free of mannans and proteins. GPs are phagocytosed by dendritic cells (DCs) via the Dectin-1 receptor, and this interaction stimulates proinflammatory cytokine secretion by...

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Detalhes bibliográficos
Main Authors: Huang, Haibin, Ostroff, Gary R., Lee, Chrono K., Specht, Charles A., Levitz, Stuart M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925077/
https://ncbi.nlm.nih.gov/pubmed/20802824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00164-10
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