Protection of mice against experimental cryptococcosis using glucan particle-based vaccines containing novel recombinant antigens

Meningitis due to Cryptococcus neoformans is responsible for upwards of 180,000 deaths worldwide annually, mostly in immunocompromised individuals. Currently there are no licensed fungal vaccines, and even with anti-fungal drug treatment, cryptococcal meningitis is often fatal. Our lab previously de...

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Bibliographische Detailangaben
Veröffentlicht in:Vaccine
Hauptverfasser: Hester, Maureen M., Lee, Chrono K., Abraham, Ambily, Khoshkenar, Payam, Ostroff, Gary R., Levitz, Stuart M., Specht, Charles A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954324/
https://ncbi.nlm.nih.gov/pubmed/31699504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2019.10.051
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