Vaccination with Recombinant Cryptococcus Proteins in Glucan Particles Protects Mice against Cryptococcosis in a Manner Dependent upon Mouse Strain and Cryptococcal Species

Development of a vaccine to protect against cryptococcosis is a priority given the enormous global burden of disease in at-risk individuals. Using glucan particles (GPs) as a delivery system, we previously demonstrated that mice vaccinated with crude Cryptococcus-derived alkaline extracts were prote...

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Publicado no:mBio
Main Authors: Specht, Charles A., Lee, Chrono K., Huang, Haibin, Hester, Maureen M., Liu, Jianhua, Luckie, Bridget A., Torres Santana, Melanie A., Mirza, Zeynep, Khoshkenar, Payam, Abraham, Ambily, Shen, Zu T., Lodge, Jennifer K., Akalin, Ali, Homan, Jane, Ostroff, Gary R., Levitz, Stuart M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5705919/
https://ncbi.nlm.nih.gov/pubmed/29184017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01872-17
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