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Protection against Experimental Cryptococcosis following Vaccination with Glucan Particles Containing Cryptococcus Alkaline Extracts

A vaccine capable of protecting at-risk persons against infections due to Cryptococcus neoformans and Cryptococcus gattii could reduce the substantial global burden of human cryptococcosis. Vaccine development has been hampered though, by lack of knowledge as to which antigens are immunoprotective a...

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Publicat a:mBio
Autors principals: Specht, Charles A., Lee, Chrono K., Huang, Haibin, Tipper, Donald J., Shen, Zu T., Lodge, Jennifer K., Leszyk, John, Ostroff, Gary R., Levitz, Stuart M.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Microbiology 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701832/
https://ncbi.nlm.nih.gov/pubmed/26695631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01905-15
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