Circulating protein synthesis rates reveal skeletal muscle proteome dynamics

Here, we have described and validated a strategy for monitoring skeletal muscle protein synthesis rates in rodents and humans over days or weeks from blood samples. We based this approach on label incorporation into proteins that are synthesized specifically in skeletal muscle and escape into the ci...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Shankaran, Mahalakshmi, King, Chelsea L., Angel, Thomas E., Holmes, William E., Li, Kelvin W., Colangelo, Marc, Price, John C., Turner, Scott M., Bell, Christopher, Hamilton, Karyn L., Miller, Benjamin F., Hellerstein, Marc K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Technical Advance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701543/
https://ncbi.nlm.nih.gov/pubmed/26657858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79639
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