Circulating protein synthesis rates reveal skeletal muscle proteome dynamics

Here, we have described and validated a strategy for monitoring skeletal muscle protein synthesis rates in rodents and humans over days or weeks from blood samples. We based this approach on label incorporation into proteins that are synthesized specifically in skeletal muscle and escape into the ci...

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Библиографические подробности
Опубликовано в: :J Clin Invest
Главные авторы: Shankaran, Mahalakshmi, King, Chelsea L., Angel, Thomas E., Holmes, William E., Li, Kelvin W., Colangelo, Marc, Price, John C., Turner, Scott M., Bell, Christopher, Hamilton, Karyn L., Miller, Benjamin F., Hellerstein, Marc K.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2015
Предметы:
Technical Advance
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701543/
https://ncbi.nlm.nih.gov/pubmed/26657858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79639
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