Circulating protein synthesis rates reveal skeletal muscle proteome dynamics

Here, we have described and validated a strategy for monitoring skeletal muscle protein synthesis rates in rodents and humans over days or weeks from blood samples. We based this approach on label incorporation into proteins that are synthesized specifically in skeletal muscle and escape into the ci...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Shankaran, Mahalakshmi, King, Chelsea L., Angel, Thomas E., Holmes, William E., Li, Kelvin W., Colangelo, Marc, Price, John C., Turner, Scott M., Bell, Christopher, Hamilton, Karyn L., Miller, Benjamin F., Hellerstein, Marc K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2015
Onderwerpen:
Technical Advance
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701543/
https://ncbi.nlm.nih.gov/pubmed/26657858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79639
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