TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress

Cellular genomes are highly vulnerable to perturbations to chromosomal DNA replication. Proliferating cell nuclear antigen (PCNA), the processivity factor for DNA replication, plays a central role as a platform for recruitment of genome surveillance and DNA repair factors to replication forks, allow...

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Bibliografske podrobnosti
izdano v:J Cell Biol
Main Authors: Hoffmann, Saskia, Smedegaard, Stine, Nakamura, Kyosuke, Mortuza, Gulnahar B., Räschle, Markus, Ibañez de Opakua, Alain, Oka, Yasuyoshi, Feng, Yunpeng, Blanco, Francisco J., Mann, Matthias, Montoya, Guillermo, Groth, Anja, Bekker-Jensen, Simon, Mailand, Niels
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2016
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700480/
https://ncbi.nlm.nih.gov/pubmed/26711499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201506071
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