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TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress
Cellular genomes are highly vulnerable to perturbations to chromosomal DNA replication. Proliferating cell nuclear antigen (PCNA), the processivity factor for DNA replication, plays a central role as a platform for recruitment of genome surveillance and DNA repair factors to replication forks, allow...
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Publicado no: | J Cell Biol |
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Main Authors: | , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Rockefeller University Press
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4700480/ https://ncbi.nlm.nih.gov/pubmed/26711499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201506071 |
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