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TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress

Cellular genomes are highly vulnerable to perturbations to chromosomal DNA replication. Proliferating cell nuclear antigen (PCNA), the processivity factor for DNA replication, plays a central role as a platform for recruitment of genome surveillance and DNA repair factors to replication forks, allow...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Hoffmann, Saskia, Smedegaard, Stine, Nakamura, Kyosuke, Mortuza, Gulnahar B., Räschle, Markus, Ibañez de Opakua, Alain, Oka, Yasuyoshi, Feng, Yunpeng, Blanco, Francisco J., Mann, Matthias, Montoya, Guillermo, Groth, Anja, Bekker-Jensen, Simon, Mailand, Niels
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4700480/
https://ncbi.nlm.nih.gov/pubmed/26711499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201506071
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